International Journal of Preventive Medicine (Int J Prev Med)2008-78024120130505139146ENIsfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Department of Medical Science, Islamic Azad University, Najafabad Branch, Isfahan, IranDepartment of Medical Science, Islamic Azad University, Najafabad Branch, Isfahan, IranIsfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Department of Neurology, Isfahan University of Medical Sciences, Isfahan, IranIsfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Department of Neurology, Isfahan University of Medical Sciences, Isfahan, IranIsfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran20130505<p>Stroke is an important cause of death in the world and disability world‑wide especially in developed countries. Following acute phase of stroke, some procedures and medical treatment such as thrombolytic agents has been recommended; nevertheless many patients have enduring deficits. Thus, there is a realistic need to develop treatment strategies for reducing neurological deficits. However, the stem cell (SC) therapy could arrange an alternative intervention for disease modifying therapy. In this article, we present a brief review of different methods of SC therapy in stroke patients and discuss the results with different cell types and routes of administration.</p> <strong>Keywords: </strong>Clinical, stem cell, stroke, treatment, trialshttp://ijpm.mui.ac.ir/index.php/ijpm/article/view/1158http://ijpm.mui.ac.ir/index.php/ijpm/article/download/1158/945