International Journal of Preventive Medicine (Int J Prev Med)2008-7802512013121199103EN20131211<p><strong>Background:</strong>This study aims to assess the relationship of serum Mg and vitamin D levels in a nationally-representative sample of Iranian adolescents.<br /><strong>Methods:</strong>The study participants consisted of 330 students, <br />aged range from 10 to 18 years, consisting of an equal number of individuals with and without hypovitaminosis D. The correlation between serum 25 hydroxy vitamin D (25(OH) D) and magnesium (Mg) concentrations was determined.<br /><strong>Results:</strong>The mean age of participants was 14.74 &plusmn; 2.587 years, without significant difference between those with hypovitaminosis D and those without it. The mean 25(OH) D level was 6.34 &plusmn; 1.47 ng/ml in the group with hypovitaminosis D and 39.27 &plusmn; 6.42 ng/ml in the&nbsp;group without it. The mean Mg level was 0.80 &plusmn; 0.23 mg/dl with <br />lower level in the group with hypovitaminosis D than in others <br />(0.73 &plusmn; 0.22 mg/dl vs. 0.87 &plusmn; 0.22 mg/dl, respectively) and <br />according to t-test analysis, significant lower levels in the deficient group was observed (P= 0.0001). The linear regression analysis showed the meaningful relationship between Mg and 25(OH) D serum levels (P= 0.0001).<br /><strong>Conclusions:</strong>Our study revealed significant associations <br />between serum Mg and 25(OH) D levels. This finding may be <br />of use for further studies on the prevention and management of hypovitaminosis D in children and adolescents. Further <br />longitudinal studies shall evaluate the underlying mechanisms and the clinical significance of the current findings.<br /><strong>Keywords</strong>:Adolescents, iran, magnesium, vitamin D</p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/1269http://ijpm.mui.ac.ir/index.php/ijpm/article/download/1269/1344