International Journal of Preventive Medicine (Int J Prev Med)2008-7802132015101015911591ENNutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran & Department of Technology Assessments, Standard and Tariff for Health, Deputy for Health Care Affair, Ministry of Health and Medical Education, TehranNutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, TehranNutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran & Department of Clinical Nutrition and Dietetic, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, TehranNutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, TehranNutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, TehranEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, TehranNutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran20151010<p><strong>Background:</strong> As food insecurity has negative effects on health, the aim of this study was to determine the relationship between household food security and type 2 diabetes mellitus and its related risk factors.</p><p><strong>Methods:</strong> In this case‑control study, 200 individuals with and 200 individuals without type 2 diabetes mellitus, aged over 40 years, were randomly selected from among participants of the Tehran Lipid and Glucose Study. The questionnaire on household food security proposed by the United States Department of Agriculture was completed for them by trained personnel. Logistic regression was used to determine the variable that had the most significant relationship with food security status.</p><p><strong>Results:</strong> The average of food security score was 2.38 &plusmn; 2.0 in non‑diabetic and 2.25 &plusmn; 2.0 in diabetic individuals (P = 0.6). In both groups, the risk for food insecurity in women was more than in men. In the diabetic group, being single and having education levels below high school increased the risk of food insecurity. In the non‑diabetic group, the risk of food insecurity in obese individuals was 3.3 times higher than normal individuals (odds ratio = 2.1, 95% confidence interval: 1.2&ndash;4.1).</p><p><strong>Conclusions:</strong> There were no significant differences in food security levels of diabetic and non‑diabetic groups. However, some risk factors of type 2 diabetes including sex, marital status, educational level, and obesity were associated with food insecurity.</p><p><strong>Keywords: </strong>Food security, obesity, Tehran Lipid and Glucose Study, type 2 diabetes mellitus</p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/1591http://ijpm.mui.ac.ir/index.php/ijpm/article/download/1591/1881