International Journal of Preventive Medicine (Int J Prev Med)2008-7802132015101315931593ENDepartment of Food Science and Technology, Shahid Beheshti University of Medical Sciences, TehranFaculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, IsfahanCenter of Excellence in Electrochemistry, Faculty of Chemistry, Tehran University20151013<p>Folic acid (FA) is a water soluble vitamin that exists in many natural species. The lack of FA causes some deficiencies in the human body, so finding a simple and sensitive method for determining the FA is important. One of the modern techniques which overcome the disadvantages of conventional determination methods is the sensors. Possibility of miniaturization, the development of microfabricated electrochemical (EC) sensors has resulted in high sensitivity, portability, improved performance and spatial resolution, low power consumption, and the opportunity for integration with other technologies made Micro‑Electrical‑Mechanical Systems‑based EC sensors suitable to identify low concentration analytes and microorganisms in a variety of mediums.</p><p><strong>Keywords:</strong> Biomaterials, folic acid, nanomaterials, selectivity, sensitivity, sensor</p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/1593http://ijpm.mui.ac.ir/index.php/ijpm/article/download/1593/1883