International Journal of Preventive Medicine (Int J Prev Med)2008-7802932018031818991899ENDepartment of Medicine, Pulmonary Unit, Isfahan University of Medical Sciences, Bamdad Respiratory Research Center, IsfahanDepartment of Internal Medicine, Isfahan University of Medical Sciences, IsfahanDepartment of Medicine, Pulmonary Unit, Isfahan University of Medical Sciences, IsfahanCenter of Sleep Medicine, Charité – Universitätsmedizin Berlin, BerlinDepartment of Cardiology and Pulmonology, Center of Sleep Medicine, Charité – Universitätsmedizin Berlin, BerlinDepartment of Cardiology and Angiology, Center of Sleep Medicine, Charité – Universitätsmedizin Berlin, BerlinDepartment of Community and Preventive Medicine, Isfahan University of Medical Sciences, Isfahan20180317<p><span class="fontstyle0"><strong>Background</strong>: </span><span class="fontstyle2">Obstructive sleep apnea (OSA) is a common disorder characterized by snoring, daytime sleepiness, fatigue, and repeated termination of airflow (apnea). Standard polysomnography (PSG) is<br />diagnostic gold standard for OSA. PSG is expensive and not available everywhere. To identify the best OSA questionnaire for screening in Persian population, we compared Berlin, STOP‑BANG, and<br />Epworth Sleepiness Scale (ESS). </span></p><p><span class="fontstyle0"><strong>Methods</strong>: </span><span class="fontstyle2">In a cross‑sectional study conducted on 400 adult patients<br />suspected of OSA in Bamdad Respiratory Research Center, patients completed three questionnaires. For each questionnaire, patients were divided into high risk and low risk. Then, PSG was performed for<br />all patients. According to PSG, patients categorized into without OSA (apnea‑hypopnea index [AHI]&lt;5), mild OSA (15&gt; AHI ≥5), moderate OSA (30&gt; AHI ≥15), and severe OSA (AHI ≥30). Based on questionnaires and PSG results, predictive parameters for screening tests were calculated. </span></p><p><strong></strong><span class="fontstyle0"><strong>Results</strong>: </span><span class="fontstyle2">There were 234 (58.5%) males and 166 (41.5%) females in study population. Mean age of patients was 49.29 ± 9.75 standard deviation years. There was signifcant association between age with<br />OSA (</span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.005) and between body mass index (BMI) and neck circumference, with moderate and severe OSA (</span><span class="fontstyle3">P </span><span class="fontstyle2">&lt; 0.001). Sensitivities of Berlin, STOP‑BANG, and ESS were 86.42%, 81.46%, and 59%, respectively. Specifcities of Berlin, STOP‑BANG, and ESS were 52.94%, 82.35%, and 76.47%, respectively. </span></p><p><span class="fontstyle0"><strong>Conclusions</strong>: </span><span class="fontstyle2">This study suggested that Berlin and STOP‑BANG are more sensitive and accurate than ESS for OSA screening in Iran.<br /></span></p><p><span class="fontstyle0" style="color: #00652e;"><strong>Keywords</strong>: </span><span class="fontstyle3">Diagnosis, obstructive sleep apnea, Persia, surveys and questionnaires</span> </p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/1899http://ijpm.mui.ac.ir/index.php/ijpm/article/download/1899/717717728