International Journal of Preventive Medicine (Int J Prev Med)2008-7802962018070719281928ENDepartment of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran & Noncommunicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, TehranDepartment of Occupational Health, School of Heath, Ahvaz Jundishapur University of Medical Sciences, AhvazDepartment of Occupational Health, School of Heath, Ahvaz Jundishapur University of Medical Sciences, AhvazDepartment of Health Services Management, School of Management and Information Sciences, Shiraz University of Medical Sciences, ShirazNoncommunicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran & Department of Epidemiology, Shahid Beheshti University of Medical Sciences, TehranNoncommunicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran & Center for Research on Occupational Diseases, Tehran University of Medical Sciences (TUMS), TehranCenter for Research on Occupational Diseases, Tehran University of Medical Sciences (TUMS), TehranDigestive Diseases Research Institute, Tehran University of Medical Sciences, TehranNoncommunicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran & Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran20180704<p><span class="fontstyle0"><strong>Background</strong>: </span><span class="fontstyle2">The present study describes the burden of occupational diseases in Iran based on the results of the Global Burden of Disease study conducted in 2010 (GBD 2010). This study aimed to determine the burden of occupational diseases in Iran based on the results of GBD 2010. It is a cross‑sectional study. </span></p><p><span class="fontstyle0"><strong>Methods</strong>: </span><span class="fontstyle2">Disability‑adjusted life years (DALYs) of occupational diseases were calculated based on the prevalence rates obtained through model estimation, as well as GBD 2010 disability weights and mortality rates obtained from different data registry systems of Iran. Causal association criteria application to select risk outcome pairs, estimation of exposure to each risk factor in the population, estimation of etiological effect size, selection of a counterfactual exposure distribution, risk assessment, and identifcation of burden attributable to each risk factor were the main conducted statistical steps. </span></p><p><span class="fontstyle0"><strong>Results</strong>: </span><span class="fontstyle2">There was an increasing trend of DALYs (710.08/100,000<br />people in 1990 and 833.00/100,000 people in 2005) followed by a slight decrease (833.00/100,000 in 2005&ndash;784.55/100,000 people in 2010). A total of 50.4% and 36% of total DALYs per 100,000 people were due to the adverse effects of musculoskeletal disorders and work‑related injuries, respectively.<br /></span></p><p><span class="fontstyle0"><strong>Conclusions</strong>: </span><span class="fontstyle2">Musculoskeletal disorders and work‑related injuries are the most important adverse consequences of work‑related risks that require urgent interventions to be controlled. Male workers (15&ndash;25 years and over 60) with the highest DALYs and mortality rates need more training programs, safety regulations, and higher level of protection support. In spite the decreasing trend of occupational disease related DALYs and death rates in Iran in recent years, a long‑term effort is<br />required to maintain the currently decreasing trend.<br /></span></p><p><span class="fontstyle0" style="color: #00652e;">Keywords: </span><span class="fontstyle3">Global burden of diseases, Iran, occupational diseases</span> <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" /></p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/1928http://ijpm.mui.ac.ir/index.php/ijpm/article/download/1928/717717753