International Journal of Preventive Medicine (Int J Prev Med)2008-78021022019021920087802ENDepartment of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, TehranDepartment of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, TehranDepartment of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, TehranDepartment of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, TehranDepartment of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, TehranDepartment of Obstetrics and Gynecology, Women’s Hospital, Tehran University of Medical Sciences, Tehran20190219<p><span class="fontstyle0"><strong>Background</strong>: </span><span class="fontstyle2">Chorionic villus sampling (CVS) and amniocentesis are two methods for prenatal diagnosis. The goal of this study was to compare amniocentesis and CVS‑related complications in a large sample of Iranian women. </span></p><p><span class="fontstyle0"><strong>Methods</strong>: </span><span class="fontstyle2">Medical records of 1624 women who underwent<br />amniocentesis or CVS due to medical indications between 2008 and 2016 were reviewed. Data regarding age, gravidity, parity, gestational age, type of procedure, neonatal weight (and percentile), trisomia, abortion, intrauterine growth restriction (IUGR), severe IUGR, preeclampsia, and<br />gestational hypertension were recorded.</span></p><p><strong></strong><span class="fontstyle0"><strong>Results</strong>: </span><span class="fontstyle2">Finally, 1215 cases were evaluated. Mean maternal age, gravidity, and gestational age were signifcantly different between two groups. Preeclampsia, gestational hypertension, IUGR, severe IUGR, and intrauterine fetal death were not signifcantly different between two groups. Trisomy 18 and 21 were common in cases underwent amniocentesis.<br /></span></p><p><span class="fontstyle0"><strong>Conclusions</strong>: </span><span class="fontstyle2">Women who underwent CVS are not at higher risk for developing hypertensive disorders than women underwent amniocentesis.<br /></span></p><p><span class="fontstyle0" style="color: #00652e;"><strong>Keywords</strong>: </span><span class="fontstyle3">Amniocentesis, chorionic villus sampling, intrauterine growth restriction, preeclampsia</span></p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2012http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2012/717717832