International Journal of Preventive Medicine (Int J Prev Med)2008-78021052019051820432043ENStudent Research Committee, Department of Occupational Health Engineering, School of Health, Shiraz University of Medical Sciences, ShirazStudent Research Committee, Department of Occupational Health Engineering, School of Health, Shiraz University of Medical Sciences, ShirazStudent Research Committee, Department of Occupational Health Engineering, School of Health, Shiraz University of Medical Sciences, ShirazStudent Research Committee, Department of Occupational Health Engineering, School of Health, Shiraz University of Medical Sciences, ShirazResearch Center for Health Sciences, Institute of Health, Shiraz University of Medical Sciences, Shiraz20190518<p><span class="fontstyle0"><strong>Background</strong>: </span><span class="fontstyle2">This study aimed to examine nurses’ job stress based on Karasek’s demand‑control‑ support model and assess its relationship with different aspects of fatigue. </span></p><p><span class="fontstyle0"><strong>Methods</strong>: </span><span class="fontstyle2">This cross‑sectional study was conducted on 522 nurses working in educational hospitals. Job stress dimensions and fatigue were measured by the Persian version of Job Content Questionnaire (JCQ) and Multidimensional<br />Fatigue Inventory (MFI), respectively. </span></p><p><span class="fontstyle0"><strong>Results</strong>: </span><span class="fontstyle2">The results showed that psychological and physical job demands obtained high scores, but social support and decision latitude got low scores. MFI results indicated that the highest score was related to the general fatigue. Moreover, the results showed a signifcant positive relationship between psychological job demands and general fatigue, but a signifcant negative correlation to reduced activity. </span></p><p><span class="fontstyle0"><strong>Conclusions</strong>: </span><span class="fontstyle2">Considering the effects of job stress on nurses’ fatigue, it is necessary to develop a suitable interventional program for nurses in healthcare<br />centers, especially hospitals, to decrease job stress and improve working conditions.<br /></span></p><p><span class="fontstyle0" style="color: #00652e;"><strong>Keywords</strong>: </span><span class="fontstyle3">Cross‑sectional studies, fatigue, job stress, nurses</span></p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2043http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2043/717717862