International Journal of Preventive Medicine (Int J Prev Med)2008-78021052019060220682068ENUniversity of Trás-os-Montes and Alto Douro, Carrazeda de Ansiães, Portugal & University Center of Itajubá, Itajubá, BrazilUniversity Center of Itajubá, ItajubáUniversity of Trásos-Montes and Alto Douro, Research Center in Sports Sciences, Health Sciences and Human Development – CIDESD, Vila Real20190602<p><span class="fontstyle0"><strong>Background</strong>: </span><span class="fontstyle2">The objective of this study was to analyze the effects of strength training on plasma homocysteine levels and cardiovascular risk factors in patients with type 2 diabetes. </span></p><p><span class="fontstyle0"><strong>Methods</strong>: </span><span class="fontstyle2">The sample consisted of 14 diabetic women with a mean age of 68 ± 6 years. Biochemical evaluations and anthropometric measurements were taken before and after training. Training sessions lasted 50 min and comprised three sets of 8–12 repetitions each. The established load was 60% of 1 repetition maximum. </span></p><p><span class="fontstyle0"><strong>Results</strong>: </span><span class="fontstyle2">After the training program, it was observed that the levels of homocysteine<br />(average before 13.4 ± 2.9 and after 12.8 ± 3.3, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.40), very low‑density lipoprotein (LDL) (average before 41.9 ± 17.0 and after 36.2 ± 11.8, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.47), total cholesterol (average before 214.4 ± 60.6 and after 190.2 ± 62.3, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.09), triglycerides (average before 209.3 ± 85.4 and after 181.5 ± 59.2, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.47), and blood glucose (average before 123.5 ± 30.4 and after 110.1 ± 24.7, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.26) showed no signifcant changes, but the LDL (average before 129.1 ± 63.4<br />and after 95.7 ± 53.3, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.04), high‑density lipoprotein (average before 43.2 ± 12.0 and after 58.2 ± 15.6, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.01), lean mass (average before 41.1 ± 5.7 and after 42.8 ± 5.4, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.008), fat mass (average before 31.4 ± 8.8 and after 29.7 ± 8.5, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.001), and percentage fat (average before 42.6 ± 4.0 and after 40.3 ± 4.6, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.000) showed signifcant changes. </span></p><p><span class="fontstyle0"><strong>Conclusions</strong>: </span><span class="fontstyle2">This study concluded that strength training does not improve homocysteine levels, but help to improve the lipoprotein profle in type 2 diabetic patients.<br /></span></p><p><span class="fontstyle0" style="color: #00652e;"><strong>Keywords</strong>: </span><span class="fontstyle3">Cholesterol, glucose, hyperhomocysteinemia, obesity, strength exercise</span></p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2068http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2068/717717886