International Journal of Preventive Medicine (Int J Prev Med)2008-78021192020102523442344ENInfectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, IsfahanNosocomial Infection Research Center, Isfahan University of Medical Sciences, IsfahanInfectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, IsfahanNosocomial Infection Research Center, Isfahan University of Medical Sciences, IsfahanDepartment of Hospitals Supervision and Accreditation, Vice-Chancellery for Clinical Affairs, Isfahan University of Medical Sciences, IsfahanInfectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, IsfahanDepartment of Microbiology, Clinical Laboratory of Alzahra Medical Center, IsfahanAlzahra Medical Center, Isfahan University of Medical Sciences, IsfahanAlzahra Medical Center, Isfahan University of Medical Sciences, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Shariati Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Shariati Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Shariati Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Shariati Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Gharazi Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Gharazi Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Gharazi Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Gharazi Hospital, Isfahan Social Security Organization, IsfahanDepartment of Microbiology, Clinical Laboratory of Alzahra Medical Center, IsfahanNosocomial Infection Research Center, Isfahan University of Medical Sciences, IsfahanDepartment of Microbiology, Clinical Laboratory of Dr. Shariati Hospital, Isfahan Social Security OrganizationDepartment of Microbiology, Clinical Laboratory of Dr. Gharazi Hospital, Isfahan Social Security Organization, IsfahanCardiovascular Department, Interventional Research Center, Isfahan University of Medical Sciences, IsfahanDepartment of Hospitals Supervision and Accreditation, Vice-Chancellery for Clinical Affairs, Isfahan University of Medical Sciences, IsfahanVice-Chancellery for Clinical Affairs, Isfahan Social Security Organization, IsfahanStudent Research Committee, Isfahan University of Medical Sciences, IsfahanChild Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan University of Medical Sciences, Isfahan20201023<p><strong>Background</strong>: Isfahan Antibiotic Resistance Surveillance System‑1 has been instituted in Isfahan, Iran to construct a project for surveillance of clinically significant bacteria, and to help raise a logic regional stewardship program for prevention and control of disseminating‑resistant organisms.</p><p><strong>Methods</strong>: During March 2016 to March 2018, an antibiotic resistance surveillance system was designed and implemented by Isfahan Infectious Diseases and Tropical Medicine Research Center. The surveillance program was implemented in three general hospitals in Isfahan. In addition to the routine microbiology data, clinical data (differentiation between true infections and contamination, healthcare‑associated infections (HCAI) and community‑acquired infections (CAI), as well as determination of the infection site) were obtained and analyzed by WHONET software.</p><p><strong>Results</strong>: During a 2‑year period, from 7056 samples that revealed growth of bacteria, 3632 (51.5%) isolates were detected as contamination and 3424 (48.5%) true bacterial isolates were identified. Of these, about 32% of isolates were recognized as HCAI. Totally, the most recognized infections were urinary tract infection, bloodstream infection and skin and soft tissue infections. In patients with HCAIs, 70% of isolates were gram negative and in patients with CAIs 73% isolates were gram negative bacteria.</p><p><strong> Conclusions</strong>: The strength of the project is gathering enough clinical information in addition to microbiologic data, which would increase application of the results for empiric treatment and prevention of the infectious diseases in clinical settings.</p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2344http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2344/717718190