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<Articles><Article><Journal><PublisherName></PublisherName><JournalTitle>International Journal of Preventive Medicine (Int J Prev Med)</JournalTitle><Issn>2008-7802</Issn><Volume>11</Volume><Issue>12</Issue><PubDate PubStatus="epublish"><Year>2021</Year><Month>03</Month><Day>17</Day></PubDate></Journal><title locale="en_US">Association of Vitamin D Deficiency with Cardiovascular Disease Among Saudi Patients in Saudi Arabia</title><FirstPage>2398</FirstPage><LastPage>2398</LastPage><Language>EN</Language><AuthorList><Author><affiliation locale="en_US">Department  of  Public  Health,  Yadam  General  Hospital,  Ministry  of  Health,  Najran</affiliation></Author><Author><affiliation locale="en_US">Department  of  Public  Health,  Yadam  General  Hospital,  Ministry  of  Health,  Najran</affiliation></Author><Author><affiliation locale="en_US">Department  of  Public  Health,  College  of  Public  Health,  Imamm  Abdul  Rehman  Bin  Faisal  University,Dammam</affiliation></Author><Author><affiliation locale="en_US">Department  of  Public  Health,  College  of  Public  Health,  Imamm  Abdul  Rehman  Bin  Faisal  University,Dammam</affiliation></Author><Author><affiliation locale="en_US">Department  of  Public  Health,  Yadam  General  Hospital,  Ministry  of  Health,  Najran</affiliation></Author><Author><affiliation locale="en_US">Department  of  Public  Health,  College  of  Public  Health,  Imamm  Abdul  Rehman  Bin  Faisal  University,Dammam</affiliation></Author></AuthorList><History><PubDate PubStatus="received"><Year>2021</Year><Month>03</Month><Day>16</Day></PubDate></History><abstract locale="en_US">&lt;p&gt;&lt;span style="left: 94.5378px; top: 236.183px; font-size: 15px; font-family: serif; transform: scaleX(1.05896);"&gt;&lt;strong&gt;Background&lt;/strong&gt;: &lt;/span&gt;&lt;span style="left: 187.019px; top: 236.183px; font-size: 15px; font-family: serif; transform: scaleX(1.03251);"&gt;Vitamin D deficiency has a far‑reaching impact on several metabolic functions &lt;/span&gt;&lt;span style="left: 94.5378px; top: 254.183px; font-size: 15px; font-family: serif; transform: scaleX(0.963043);"&gt;including cardiovascular health. This study aimed to test the association of serum 25 [OH]‑vitamin &lt;/span&gt;&lt;span style="left: 94.5378px; top: 272.183px; font-size: 15px; font-family: serif; transform: scaleX(1.0074);"&gt;D3 levels among cardiovascular disease (i.e., hypertension and ischemic heart disease) patients. &lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span style="left: 94.5378px; top: 290.183px; font-size: 15px; font-family: serif; transform: scaleX(1.04925);"&gt;&lt;strong&gt;Methods&lt;/strong&gt;: &lt;/span&gt;&lt;span style="left: 162.822px; top: 290.183px; font-size: 15px; font-family: serif; transform: scaleX(1.00463);"&gt;A cross‑sectional study was conducted among 360 participants from the tertiary care &lt;/span&gt;&lt;span style="left: 94.5378px; top: 308.183px; font-size: 15px; font-family: serif; transform: scaleX(0.994013);"&gt;hospital. The simple random technique was used to select the participants. Only Saudi nationals &lt;/span&gt;&lt;span style="left: 94.5378px; top: 326.183px; font-size: 15px; font-family: serif; transform: scaleX(0.962994);"&gt;were included in the study. Sociodemographic information, nutritional status, biochemical parameter &lt;/span&gt;&lt;span style="left: 94.5378px; top: 344.183px; font-size: 15px; font-family: serif; transform: scaleX(0.994833);"&gt;(lipid profile, blood glucose level), and questions relating to cardiovascular disease were collected from &lt;/span&gt;&lt;span style="left: 94.5378px; top: 362.183px; font-size: 15px; font-family: serif; transform: scaleX(1.00547);"&gt;the hospital record through data collection sheet. Serum Vit D level was determined by serum 25 &lt;/span&gt;&lt;span style="left: 681.863px; top: 362.183px; font-size: 15px; font-family: serif; transform: scaleX(1.01393);"&gt;(OH) &lt;/span&gt;&lt;span style="left: 94.5378px; top: 380.183px; font-size: 15px; font-family: serif; transform: scaleX(1.00008);"&gt;blood test. Statistical package for social science (SPSS) software version 24 was used for data analysis. &lt;/span&gt;&lt;span style="left: 94.5378px; top: 398.183px; font-size: 15px; font-family: serif; transform: scaleX(1.01434);"&gt;Binary logistic regression model was fitted to indentify the associated factors of vitamin D deficiency &lt;/span&gt;&lt;span style="left: 94.5378px; top: 416.183px; font-size: 15px; font-family: serif; transform: scaleX(0.93823);"&gt;among cardiovascular disease patients. &lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span style="left: 330.853px; top: 416.183px; font-size: 15px; font-family: serif; transform: scaleX(1.04436);"&gt;&lt;strong&gt;Results&lt;/strong&gt;:&lt;/span&gt;&lt;span style="left: 381.318px; top: 416.183px; font-size: 15px; font-family: serif; transform: scaleX(0.922613);"&gt; Approximately 40.6% and 27.8% of study participants &lt;/span&gt;&lt;span style="left: 94.5378px; top: 434.183px; font-size: 15px; font-family: serif; transform: scaleX(0.994435);"&gt;had vitamin D deficiency and insufficiency, respectively. After adjustment of covariates, among cardiac &lt;/span&gt;&lt;span style="left: 94.5378px; top: 452.183px; font-size: 15px; font-family: serif; transform: scaleX(0.985039);"&gt;patients, vitamin D deficiency was associated with ischemic heart disease &lt;/span&gt;&lt;span style="left: 533.438px; top: 452.183px; font-size: 15px; font-family: serif; transform: scaleX(0.988988);"&gt;(OR 2.24, 95% CI 1.11–4.52), &lt;/span&gt;&lt;span style="left: 94.5378px; top: 470.183px; font-size: 15px; font-family: serif; transform: scaleX(0.962415);"&gt;and blood triglyceride level &lt;/span&gt;&lt;span style="left: 270.968px; top: 470.183px; font-size: 15px; font-family: serif; transform: scaleX(0.961686);"&gt;(OR 2.27, 95% CI 1.22–4.22). &lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span style="left: 467.016px; top: 470.183px; font-size: 15px; font-family: serif; transform: scaleX(1.03062);"&gt;&lt;strong&gt;Conclusions&lt;/strong&gt;:&lt;/span&gt;&lt;span style="left: 547.738px; top: 470.183px; font-size: 15px; font-family: serif; transform: scaleX(0.954992);"&gt; Vitamin D deficiency and &lt;/span&gt;&lt;span style="left: 94.5378px; top: 488.183px; font-size: 15px; font-family: serif; transform: scaleX(0.987897);"&gt;insufficiency are associated with ischemic heart disease, hyperglycemia, and hypertriglyceridemia. &lt;/span&gt;&lt;span style="left: 94.5378px; top: 506.183px; font-size: 15px; font-family: serif; transform: scaleX(0.913893);"&gt;There is a need for the screening of cardiovascular disease patients for vitamin D levels.&lt;/span&gt;&lt;/p&gt;</abstract><web_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2398</web_url><pdf_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2398/717718241</pdf_url></Article></Articles>
