International Journal of Preventive Medicine (Int J Prev Med)2008-78021120110918268268ENAssociate Professor of Nutritional Sciences, Department of Nutrition, Tehran University of Medical Sciences. Tehran, IranMaster Degree in Nutrition Sciences, Department of Nutrition, Tehran University of Medical Sciences. Tehran, IranAssociate Professor of Nutritional Sciences, Department of Nutrition, Tehran University of Medical Sciences. Tehran, IranAssociate Professor Department of Pharmacognosy, Tehran University of Medical Sciences.Associate Professor, Department of Endocrinology ,Tehran University of Medical Sciences. Tehran, IranAssistance Professor, Department of Epidemiology and biostatistics, Tehran University of Medical Sciences. Tehran, IranMaster Degree in Nutrition Sciences, PhD Candidate in Nutrition Sciences, Department of Nutrition, Tehran University of Medical Sciences. Tehran, Iran201107222011091620110916<p><strong>Objective: </strong>Type 2 diabetes is the most common metabolic disorder worldwide. Traditional herbs and spices can be used to control blood glucose concentrations. The objective of this study was to evaluate the effects of the daily intake of three grams cinnamon over eight weeks on glycemic status, lipid profiles and body composition in type 2 diabetic patients.</p> <p><strong>Methods: </strong>A double blind, randomized, placebo controlled clinical trial was conducted on 44 patients with type 2 diabetes. Participants were randomly assigned to take either a three g/ day cinnamon supplement (<em>n</em>=22) or a placebo (<em>n</em>=22) for eight weeks. Weight, height, body fat mass and systolic and diastolic blood pressure were measured at baseline and after intervention. The fasting blood glucose, insulin, HbA1c, total cholesterol, LDL C, HDL C, Apo lipoprotein A I and B were measured at baseline and endpoint.</p> <p><strong>Results: </strong>From 44 subjects participated in this study 37 completed the study. There were no significant differences in baseline characteristics, dietary intake and physical activity between groups. In the treatment group, the levels of fasting blood glucose, HbA1c, triglyceride, weight, BMI and body fat mass decreased significantly compared to baseline, but not in placebo group. No significant differences were observed in glycemic status indicators, lipid profile and anthropometric indicators between the groups at the end of intervention.</p> <p><strong>Conclusion: </strong>These data suggest that cinnamon may have a</p> <p>moderate effect in improving glycemic status indicators.</p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/268http://ijpm.mui.ac.ir/index.php/ijpm/article/download/268/622