International Journal of Preventive Medicine (Int J Prev Med)2008-780213102022112327232723ENDepartment of Community Medicine, School of Medicine & Health Behavior Science Research Center, Shiraz University of Medical Sciences and Health Services, ShirazGeneral and Community Pediatrics, Children’s National Hospital, 111 Michigan Ave., NW, Washington, DC 20010Student Research Committee, School of Medicine, Shiraz University of Medical Sciences and Health Services, ShirazTrauma Research Center, Shahid Rajaee (Emtiaz) Trauma Hospital, Shiraz University of Medical Sciences, ShirazTrauma Research Center, Department of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, ShirazMedical Student, School of Medicine, Shiraz University of Medical Sciences and Health Services, ShirazMedical Student, School of Medicine, Shiraz University of Medical Sciences and Health Services, ShirazStudent Research Committee, School of Medicine, Shiraz University of Medical Sciences and Health Services, ShirazDepartment of Medicine, Jewish General Hospital, McGill University, MontrealStudent, College of Arts & Science, University of Saskatchewan, SaskatoonStudent Research Committee, School of Medicine, Shiraz University of Medical Sciences and Health Services, Shiraz20221123<p><strong>Background</strong>: In the name of extensive vaccine uptake, understanding the public’s attitude, perception, and intent toward COVID‑19 vaccination is a significant challenge for public health officials.</p><p><strong>Methods</strong>: A cross‑sectional survey via an online questionnaire rooted in the Health Belief Model and Integrated Behavioral Model was conducted to evaluate COVID‑19 vaccination intent and its associated factors. Factor analysis and multivariate logistic regression were operated to be satisfactory.</p><p><strong>Results</strong>: Among the 4,933 respondents, 24.7% were health care workers, and 64.2% intended to accept COVID‑19 vaccination. The adjusted odds (aOR) of COVID‑19 vaccination intent was higher for individuals with greater exposure to social norms supportive of COVID‑19 vaccination (aOR = 3.07, 95% Confidence Interval (CI) = 2.71, 3.47) and higher perceived benefits of COVID‑19 vaccination (aOR = 2.9, 95% CI = 2.49, 3.38). The adjusted odds of vaccination intent were lower for individuals with greater COVID‑19 vaccine safety concerns (aOR = 0.28, 95%CI = 0.25, 0.31). Lower vaccination intent was also associated with increasing age ((aOR = 0.99, 95% CI = 0.98, 0.999), female sex (aOR = 0.76, 95% CI = 0.65, 0.88), and working in the health care field (aOR = 0.75, 95% CI = 0.63, 0.9).</p><p><strong>Conclusions</strong>: The odds of COVID‑19 vaccination intent were higher three or more times among those with a greater belief in vaccine effectiveness, lower concerns about vaccine safety, and greater exposure to cues to vaccinate, including from doctors. This last finding is concerning as vaccine acceptance was surprisingly lower among health care workers compared to others. The remarkable results of factor analysis and reliability of the questionnaire may encourage local health authorities to apply it to their regional population.</p>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2723http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2723/717718564