International Journal of Preventive Medicine (Int J Prev Med)2008-78021462023073028292829ENPrivate Academic Consultant, BangkokDepartment of Community Medicine, Dr. D. Y. Patil University, Pune, Maharashtra20230722Dear Editor, COVID‑19 vaccine is the preventive tool against COVID‑19. The safety of the new vaccine is the present issue for research. For any vaccination, postvaccination death requires a good investigation. An interesting emerging problem on postvaccination death due to ruptured aneurysms is an interesting observation. The primary investigation by local public health administrators usually reveals no association (for example, see https://healthserv.net/en9417). Theoretically, COVID‑19 might cause aberration in homoeostatic system. The clinical association with an aneurysm is also reported.http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2829http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2829/717718712