International Journal of Preventive Medicine (Int J Prev Med)2008-780214201011025656ENMSc of Exercise Sciences, Department of Exercise Sciences, Kazeroun University of Payam Nour, Kazeroun.BS of Exercise Sciences, Education and Training Organization, Darab.PhD of Exercise Sciences, Department of Exercise Sciences, Shiraz University, Shiraz.PhD, Professor of Sport Medicine, Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, USA, and Department of Exercise Sciences, University of Isfahan, Isfahan.Assistant Professor of Exercise Physiology; Faculty of Physical Education and Sports Sciences, University of Isfahan.20101107ABSTRACT<br />Objectives: The aim of this study was to investigate the relation<br />between C-reactive protein (CRP) with physical fitness, physical<br />activity, obesity, and selected cardiovascular risk factors in schoolchildren.<br />Methods: Forty-four boy schoolchildren (mean &plusmn; SD: age 10.25<br />&plusmn; 0.75 years, height 144 &plusmn; 0.2 cm, body weight 46.1 5&plusmn; 4.59 kg,<br />body mass index 22.16 &plusmn; 2.16 kg/m2) voluntarily participated in<br />this study. Physical fitness and physical activity were assessed using<br />the 20-meter fitness test. Adiposity was estimated using body mass<br />index. Blood samples were taken after an overnight fast and measured<br />for CRP, LDL, HDL and cholesterol. Pearson&rsquo;s correlation<br />was calculated to determine the relations between these factors.<br />Results: Mean (SD) CRP concentration was 1.07 (0.82) mg/l. A<br />significant correlation was observed between CRP and VO2max<br />(r=-0.45, P= 0.001), body mass index (r=0.55, P=0.000) and cholesterol<br />(r=-0.35, P=0.04). No significant relation was found between<br />CRP and physical activity, LDL and HDL (P&gt; 0.05).<br />Moreover, significant associations were observed between body<br />mass index and VO2max (r=-0.33, P=0.02) and physical activity<br />(r=-0.43, P=0.04).<br />Conclusions: Body mass index was the most powerful predictor<br />of serum concentrations of CRP in schoolchildren. It may be an<br />important factor to control body weight to prevent an increase in<br />serum CRP in children and to help the primordial prevention of<br />chronic diseases.<br />Keywords: Cardiovascular diseases, C-reactive protein, Fitness,<br />Body mass index.http://ijpm.mui.ac.ir/index.php/ijpm/article/view/56http://ijpm.mui.ac.ir/index.php/ijpm/article/download/56/303