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<Articles><Article><Journal><PublisherName></PublisherName><JournalTitle>International Journal of Preventive Medicine (Int J Prev Med)</JournalTitle><Issn>2008-7802</Issn><Volume>15</Volume><Issue>4</Issue><PubDate PubStatus="epublish"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></Journal><title locale="en_US">Association of Prior COVID‑19 Infection with Risk of Breakthrough Infection Following Vaccination: A Cohort Study in Isfahan, Iran</title><FirstPage>1</FirstPage><LastPage>10</LastPage><Language>EN</Language><AuthorList><Author><affiliation locale="en_US">Cancer Prevention Research Center, Omid Hospital, Isfahan University of Medical Sciences, Isfahan</affiliation></Author><Author><affiliation locale="en_US">Craniofacial and Cleft Research Center, Isfahan University of Medical Sciences, Isfahan</affiliation></Author><Author><affiliation locale="en_US">Department of Epidemiology and Biostatistics, Health School, Isfahan University of Medical Sciences, Isfahan</affiliation></Author><Author><affiliation locale="en_US">Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan</affiliation></Author></AuthorList><History><PubDate PubStatus="received"><Year>2024</Year><Month>07</Month><Day>24</Day></PubDate></History><abstract locale="en_US">&lt;p&gt;Background: Many people worldwide have developed a combination of natural and vaccine‑induced immunity to COVID‑19. This study investigated whether exposure to SARS‑CoV‑2 before full vaccination promotes protection against a breakthrough infection. Methods: We studied a total of 2,902,545 people in the Isfahan COVID‑19 Registry. All the participants had received two doses of either Sinopharm BIBP, ChAdOx1‑nCoV‑19, Gam‑COVID‑Vac, or BIV1‑CovIran vaccines. A cohort study examined the association between prior COVID‑19 infection and the risk of a breakthrough infection for each vaccine. Cohorts in each pair were matched by gender, age group, calendar week of the first dose, the interval between the first and second doses, and the proportion of healthcare workers. The probable virus variant for the previous infections was also considered. Each individual’s follow‑up started 14 days after their second vaccine dose until either the end of the study censoring date, occurrence of a COVID‑19 infection, or death. The breakthrough infection risk was compared between each cohort pair by using the hazard ratio (HR) and incidence rate ratio (IRR). Results: Total breakthrough HRs (95% confidence interval) (previously infected over infection‑naïve matched cohort) were 0.36 (0.23–0.55), 0.35 (0.32–0.40), 0.37 (0.30–0.46), and 0.43 (0.32–0.56) for the BIV1‑CovIran, Sinopharm BIBP, Gam‑COVID‑Vac, and ChAdOx1‑nCoV‑19 vaccine groups, respectively. The breakthrough infection IRRs were approximately similar to the total HRs mentioned above. Conclusion: Prior SARS‑CoV‑2 infection conferred additive immunity against breakthrough after vaccination, no matter which vaccine brand was injected. Such a result could guide health authorities to codify low‑cost high‑benefit vaccination protocols and protect the community’s well‑being.&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt;&lt;span class="ej-journal-name" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;International Journal of Preventive Medicine&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span id="ej-journal-date-volume-issue-pg" style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;a style="box-sizing: border-box; color: #005b92; text-decoration: none; background-color: transparent; cursor: pointer; outline: 0px;" href="https://journals.lww.com/ijom/pages/currenttoc.aspx"&gt;15():18, April 2024.&lt;/a&gt;&lt;/span&gt;&lt;span style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;span&gt; &lt;/span&gt;|&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span class="ej-journal-doi" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;DOI:&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;10.4103/ijpvm.ijpvm_173_23&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Corresponding Authors:&lt;/p&gt;&lt;p&gt;&lt;span class="fontstyle0"&gt;Dr. Maryam Nasirian&lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span class="fontstyle0"&gt;E‑mail: &lt;span class="fontstyle0"&gt;maryamnasirian17@gmail.com&lt;/span&gt; &lt;br /&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span class="fontstyle0"&gt;&lt;span class="fontstyle0"&gt;You can also search for this author in: &lt;a title="PubMed" href="https://pubmed.ncbi.nlm.nih.gov/?term=%28maryam+nasirian%5BAuthor%5D%29+AND+%28Isfahan+University+of+Medical+Sciences%5BAffiliation%5D%29&amp;amp;sort="&gt;PubMe&lt;/a&gt;d &lt;a title="Google Scholar" href="https://scholar.google.com/citations?user=sE51tGkAAAAJ&amp;amp;hl=en&amp;amp;oi=ao"&gt;Google Scholar&lt;/a&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span class="fontstyle0"&gt;&lt;span class="fontstyle0"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span class="fontstyle0"&gt;&lt;span class="fontstyle0"&gt;Dr. Shaghayegh Haghjooy Javanmard&lt;/span&gt; &lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span class="fontstyle0"&gt;&lt;span class="fontstyle0"&gt;E‑mail:&lt;/span&gt; shaghayegh.haghjoo@gmail.com&lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span class="fontstyle0"&gt;You can also search for this author in: &lt;span class="fontstyle0"&gt;&lt;span class="fontstyle0"&gt;&lt;a title="PubMed" href="/index.php/ijpm/author/saveSubmit/(Haghjooy%20Javanmard%20S[Author])%20AND%20(Isfahan%20University%20of%20Medical%20Sciences[Affiliation])"&gt;PubMed&lt;/a&gt; &lt;a title="Google Scholar" href="https://scholar.google.com/citations?user=kcM11Z8AAAAJ&amp;amp;hl=en&amp;amp;oi=sra"&gt;Google Scholar&lt;/a&gt;&lt;/span&gt;&lt;/span&gt;&lt;br /&gt;&lt;/span&gt;&lt;/p&gt;</abstract><web_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2908</web_url><pdf_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2908/717718749</pdf_url></Article><Article><Journal><PublisherName></PublisherName><JournalTitle>International Journal of Preventive Medicine (Int J Prev Med)</JournalTitle><Issn>2008-7802</Issn><Volume>15</Volume><Issue>4</Issue><PubDate PubStatus="epublish"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></Journal><title locale="en_US">Solitary Functioning Kidneys Attenuate Renal Hemodynamics Responses to Angiotensin II in Male But Not in Female Rats</title><FirstPage>11</FirstPage><LastPage>15</LastPage><Language>EN</Language><AuthorList><Author><affiliation locale="en_US">Department of Physiology, Isfahan University of Medical Sciences, Isfahan</affiliation></Author><Author><affiliation locale="en_US">Water and Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan</affiliation></Author></AuthorList><History><PubDate PubStatus="received"><Year>2024</Year><Month>07</Month><Day>24</Day></PubDate></History><abstract locale="en_US">&lt;p&gt;Backgrounds: People with solitary functioning kidneys (SFK) are prone to renal failure with time. Accordingly, local renin angiotensin system (RAS) and renal functions in subjects with SFK may act differently compared to normal condition. This study was designed to determine the renal hemodynamics responses to angiotensin II (Ang. II) in SFK male and female rats. Methods: Fifty to sixty‑day‑old male and female Wistar rats were subjected to unilateral renal artery obstruction, and 28 days later basal renal hemodynamic responses to Ang. II were examined in SFK groups compared to sham groups. Results: The findings indicated lower renal vascular resistance (RVR) and renal blood flow (RBF) responses to Ang. II in male SFK compared to sham group. Such observation was not seen in female animals. Conclusions: An increase in renal metabolism due to hyperfunction, especially in SFK male rats, may cause a decrease in RVR. Moreover, the lower RBF response to Ang. II may be related to alteration to Ang. II receptors in the remnant kidneys in SFK rats.&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt;&lt;span class="ej-journal-name" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;International Journal of Preventive Medicine&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span id="ej-journal-date-volume-issue-pg" style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;a style="box-sizing: border-box; color: #005b92; text-decoration: none; background-color: transparent; cursor: pointer; outline: 0px;" href="https://journals.lww.com/ijom/pages/currenttoc.aspx"&gt;15():19, April 2024.&lt;/a&gt;&lt;/span&gt;&lt;span style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;span&gt; &lt;/span&gt;|&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span class="ej-journal-doi" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;DOI:&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;10.4103/ijpvm.ijpvm_195_23&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Corresponding Author: &lt;span class="fontstyle0"&gt;Dr. Mehdi Nematbakhsh&lt;/span&gt;&lt;/p&gt;&lt;p&gt;E‑mail: &lt;span class="fontstyle0"&gt;nematbakhsh@med.mui.ac.ir&lt;/span&gt;&lt;/p&gt;&lt;p&gt;You can also search for this author in: &lt;a title="PubMed" href="https://pubmed.ncbi.nlm.nih.gov/?term=%28Mehdi+Nematbakhsh%5BAuthor%5D%29+AND+%28Isfahan+University+of+Medical+Sciences%5BAffiliation%5D%29"&gt;PubMed&lt;/a&gt; &lt;a title="Google Scholar" href="https://scholar.google.com/citations?user=1fkyPt8AAAAJ&amp;amp;hl=en&amp;amp;oi=ao"&gt;Google Scholar&lt;/a&gt;&lt;/p&gt;</abstract><web_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2909</web_url><pdf_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2909/717718750</pdf_url></Article><Article><Journal><PublisherName></PublisherName><JournalTitle>International Journal of Preventive Medicine (Int J Prev Med)</JournalTitle><Issn>2008-7802</Issn><Volume>15</Volume><Issue>4</Issue><PubDate PubStatus="epublish"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></Journal><title locale="en_US">Advancing Diabetes Self‑Management: A Novel Smartphone Application Featuring a Scoring Algorithm for Tailored User Engagement</title><FirstPage>16</FirstPage><LastPage>22</LastPage><Language>EN</Language><AuthorList><Author><affiliation locale="en_US">Department of Computer Software Engineering, South Tehran Branch, Islamic Azad University, Tehran</affiliation></Author><Author><affiliation locale="en_US">Department of Clinical Nutrition, School of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran</affiliation></Author></AuthorList><History><PubDate PubStatus="received"><Year>2024</Year><Month>07</Month><Day>24</Day></PubDate></History><abstract locale="en_US">&lt;p&gt;Background: We developed and evaluated an intelligent diabetes assistant application (Diabetter) for the self‑management of diabetes. It suggested that increasing the patient’s interest and participation in using smartphone apps is important for the effectiveness of diabetes management apps. Methods: After evaluating all‑encompassing features for diabetes management, we divided the selected factors into sub-factors for use in the application. Then, we created the first high‑fidelity prototype using related programs and conducted early user testing to validate and improve Diabetter. To handle the user transaction time and keep them motivated, we designed and implemented a scoring system based on the nudge theory rules within the app. Results: To evaluate Diabetter’s impact on diabetes self‑management, we measured HbA1c levels after a prolonged period. The Diabetter prototype was developed and modified in a revised version for better user interaction with the app. The scoring system increased the input of users’ information, which resulted in more analysis and recommendations to users. Clinical studies showed that as a result of continuous input of information from users who had been using the application for a longer period of time, their HbA1c levels were within the healthy range. Conclusions: The results demonstrate that the Diabetter application has been able to play an effective role in diabetes self‑management by increasing users’ app usage time. However, future study is needed to provide a better interpretation.&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt;&lt;span class="ej-journal-name" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;International Journal of Preventive Medicine&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span id="ej-journal-date-volume-issue-pg" style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;a style="box-sizing: border-box; color: #005b92; text-decoration: none; background-color: transparent; cursor: pointer; outline: 0px;" href="https://journals.lww.com/ijom/pages/currenttoc.aspx"&gt;15():20, April 2024.&lt;/a&gt;&lt;/span&gt;&lt;span style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;span&gt; &lt;/span&gt;|&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span class="ej-journal-doi" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;DOI:&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;10.4103/ijpvm.ijpvm_268_23&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Corresponding Author: Dr. Mohammad A. Tebianian&lt;/p&gt;&lt;p&gt;Email: tebianianmohammadamin@gmail.com&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt; &lt;/p&gt;</abstract><web_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2910</web_url><pdf_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2910/717718751</pdf_url></Article><Article><Journal><PublisherName></PublisherName><JournalTitle>International Journal of Preventive Medicine (Int J Prev Med)</JournalTitle><Issn>2008-7802</Issn><Volume>15</Volume><Issue>4</Issue><PubDate PubStatus="epublish"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></Journal><title locale="en_US">Mutation Analysis of PAH Gene in Phenylketonuria Patients from the North of Iran: Identification of Three Novel Pathogenic Variants</title><FirstPage>23</FirstPage><LastPage>27</LastPage><Language>EN</Language><AuthorList><Author><affiliation locale="en_US">Thalassemia Research Center, Hemoglobinopathies Institute, Mazandaran University of Medical Sciences, Sari</affiliation></Author><Author><affiliation locale="en_US">Diabetes Research Center, Mazandaran University of Medical Sciences, Sari</affiliation></Author><Author><affiliation locale="en_US">Sinaye Mehr Research Center, Sari</affiliation></Author><Author><affiliation locale="en_US">Sinaye Mehr Research Center, Sari</affiliation></Author><Author><affiliation locale="en_US">Sinaye Mehr Research Center, Sari</affiliation></Author><Author><affiliation locale="en_US">Thalassemia Research Center, Hemoglobinopathies Institute, Mazandaran University of Medical Sciences, Sari</affiliation></Author></AuthorList><History><PubDate PubStatus="received"><Year>2024</Year><Month>07</Month><Day>24</Day></PubDate></History><abstract locale="en_US">&lt;p&gt;Background: There are more than 1100 different pathogenic variants in the phenylalanine hydroxylase (PAH) gene that are responsible for phenylketonuria (PKU) diseases, and the spectrum of these mutations varies in different ethnic groups. The aim of the present study was to identify the frequency of pathogenic variants in all 13 exons of the PAH gene among patients with PKU in Mazandaran and Golestan provinces in the north of Iran. Methods: Forty unrelated PKU patients from Mazandaran and Golestan provinces were enrolled in the study. Genomic DNA was extracted from leukocytes using a Qiagen DNA extraction kit and polymerase chain reaction – restriction fragment length polymorphism (PCR‑RFLP), and Sanger sequencing methods were applied to detect the variants. In the case of new variants, the InterVar online tool (PMID: 28132688) was used to classify the variants. Results: Twenty‑one different pathogenic variants were observed among the 40 investigated patients. The c.106611G&amp;gt;A variant had the highest frequency (27.5%) in the region, and the c.168+5G&amp;gt;C, c.473G&amp;gt;A, and c.782 G&amp;gt;A variants were the other most frequent mutations with allelic frequencies of 7.5, 5, and 5%, respectively. Three novel pathogenic variants including c.773T&amp;gt;G, c.878 T&amp;gt;C, and c. 1245del variants were observed among the investigated patients. Conclusions: The introduction of pathogenic variants in the PAH gene in each ethnic group provides valuable data regarding the understanding of the pathogenesis of the disease and can be helpful for prenatal diagnosis programs.&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt;&lt;span class="ej-journal-name" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;International Journal of Preventive Medicine&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span id="ej-journal-date-volume-issue-pg" style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;a style="box-sizing: border-box; color: #005b92; text-decoration: none; background-color: transparent; cursor: pointer; outline: 0px;" href="https://journals.lww.com/ijom/pages/currenttoc.aspx"&gt;15():22, April 2024.&lt;/a&gt;&lt;/span&gt;&lt;span style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;span&gt; &lt;/span&gt;|&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span class="ej-journal-doi" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;DOI:&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;10.4103/ijpvm.ijpvm_50_23&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Corresponding Author: Dr. Mohammad Reza Mahdavi&lt;/p&gt;&lt;p&gt;E‑mail: Mahdavi899@gmail.com&lt;/p&gt;&lt;p&gt;You can also search for this author in: &lt;a title="PubMed" href="https://pubmed.ncbi.nlm.nih.gov/?term=%28Mazandaran+University+of+Medical+Sciences%5BAffiliation%5D%29+AND+%28Mohammad+Reza+Mahdavi+Amiri%5BAuthor%5D%29&amp;amp;sort="&gt;PubMed&lt;/a&gt; &lt;a title="Google Scholar" href="https://scholar.google.com/citations?hl=en&amp;amp;user=FUd2sf0AAAAJ"&gt;Google Scholar&lt;/a&gt;&lt;/p&gt;</abstract><web_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2911</web_url><pdf_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2911/717718752</pdf_url></Article><Article><Journal><PublisherName></PublisherName><JournalTitle>International Journal of Preventive Medicine (Int J Prev Med)</JournalTitle><Issn>2008-7802</Issn><Volume>15</Volume><Issue>4</Issue><PubDate PubStatus="epublish"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></Journal><title locale="en_US">Role of Branched and Aromatic Amino Acids, Diet Inflammatory Index, and Anthropometric Indices on Mental Health</title><FirstPage>28</FirstPage><LastPage>36</LastPage><Language>EN</Language><AuthorList><Author><affiliation locale="en_US">Department of Nutrition, Science and Research Branch Islamic Azad University, Tehran</affiliation></Author><Author><affiliation locale="en_US">Department of Nutrition, Science and Research Branch Islamic Azad University, Tehran</affiliation></Author><Author><affiliation locale="en_US">Department of Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran</affiliation></Author><Author><affiliation locale="en_US">Department of Nutrition, Science and Research Branch Islamic Azad University, Tehran</affiliation></Author></AuthorList><History><PubDate PubStatus="received"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></History><abstract locale="en_US">&lt;p&gt;Background: Mental health disorders are one of the most important and increasing health problems in the youth of today’s societies. Some dietary intake and body mass status are factors that affect mental health. This study aimed to investigate the relationship between the intake of branched‑chain amino acids (BCAAs) and aromatic amino acids (AAAs) and anthropometric and dietary inflammatory indices with mental health, including depression, anxiety, and stress. Methods: In this case‑control study, the data of 138 teenage girls aged 13–18 years were collected. Three‑day 24‑hour food recall and standard anthropometric methods were used to calculate the dietary inflammation intake score of normal and energy‑adjusted diets. Mental health disorders were diagnosed by the DASS‑21 questionnaire. Statistical analysis used Student’s t‑test, correlation, and multiple regression were used to analyze the data based on the study’s statistical requirements. Results: Based on the findings, 59 (42%) of the girls had mental disorders, and 79 (58%) were healthy. The average weight of stressed people was significantly higher than that of healthy people, and the BMI of anxious people was significantly higher than that of nonanxious people (P &amp;lt; 0.05). A significant positive correlation was found between stress and weight and energy intake. Additionally, there was a significant negative correlation between BCAAs and mental health. The average intake of BCAAs was significantly lower in patients (P = 0.01). The trend analysis showed significantly lower BCAA levels among the 4th quartile of mental disorders. No significant relationship was observed between DII, AAA, and anthropometric indices. After adjustment of the results, no relationship was observed between mental health and the studied factors. Conclusions: BCAA might be related to mental health. Further studies in different age and sex groups are highly recommended.&lt;/p&gt;&lt;p&gt;&lt;span class="ej-journal-name" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;br /&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span class="ej-journal-name" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;International Journal of Preventive Medicine&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span id="ej-journal-date-volume-issue-pg" style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;a style="box-sizing: border-box; color: #005b92; text-decoration: none; background-color: transparent; cursor: pointer; outline: 0px;" href="https://journals.lww.com/ijom/toc/2024/04000"&gt;15():23, April 2024.&lt;/a&gt;&lt;/span&gt;&lt;span style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;span&gt; &lt;/span&gt;|&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span class="ej-journal-doi" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;DOI:&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;10.4103/ijpvm.ijpvm_59_23&lt;/span&gt;&lt;/p&gt;&lt;p&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;Corresponding Author: Dr. Ariyo Movahedi&lt;br /&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt;E‑mail:amm35@mail.aub.edu&lt;/p&gt;&lt;p&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;You can also search for this author in: &lt;a title="PubMed" href="https://pubmed.ncbi.nlm.nih.gov/?term=%28Ariyo+Movahedi%5BAuthor%5D%29+AND+%28+Islamic+Azad+University%5BAffiliation%5D%29"&gt;PubMed&lt;/a&gt;  &lt;a title="Google Scholar" href="https://scholar.google.com/citations?user=Laq4YPQAAAAJ&amp;amp;hl=en&amp;amp;oi=ao"&gt;Google Scholar&lt;/a&gt;&lt;br /&gt;&lt;/span&gt;&lt;/p&gt;</abstract><web_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2912</web_url><pdf_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2912/717718753</pdf_url></Article><Article><Journal><PublisherName></PublisherName><JournalTitle>International Journal of Preventive Medicine (Int J Prev Med)</JournalTitle><Issn>2008-7802</Issn><Volume>15</Volume><Issue>4</Issue><PubDate PubStatus="epublish"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></Journal><title locale="en_US">Sustainable Development and the Battle against Non‑Communicable Diseases (NCDs)</title><FirstPage>37</FirstPage><LastPage>38</LastPage><Language>EN</Language><AuthorList><Author><affiliation locale="en_US">Department of Community Health Nursing, Teerthanker Mahaveer University, College of Nursing, Moradabad, Uttar Pradesh</affiliation></Author></AuthorList><History><PubDate PubStatus="received"><Year>2024</Year><Month>08</Month><Day>11</Day></PubDate></History><abstract locale="en_US">&lt;p&gt;Dear Editor, I am writing to express my concern regarding the increasing burden of non‑communicable diseases (NCDs) and the crucial role that sustainable development can play in addressing this global health challenge.&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt;&lt;span class="ej-journal-name" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;International Journal of Preventive Medicine&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span id="ej-journal-date-volume-issue-pg" style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;a style="box-sizing: border-box; color: #005b92; text-decoration: none; background-color: transparent; cursor: pointer; outline: 0px;" href="https://journals.lww.com/ijom/toc/2024/04000"&gt;15():21, April 2024.&lt;/a&gt;&lt;/span&gt;&lt;span style="box-sizing: inherit; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;&lt;span&gt; &lt;/span&gt;|&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span class="ej-journal-doi" style="box-sizing: inherit; font-style: italic; font-weight: 500; color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-variant-ligatures: normal; font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"&gt;DOI:&lt;span&gt; &lt;/span&gt;&lt;/span&gt;&lt;span style="color: #3b3030; font-family: 'Fira Sans', sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;"&gt;10.4103/ijpvm.ijpvm_334_23&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Corresponding Author: Dr. Ram Kumar Garg&lt;/p&gt;&lt;p&gt;E-mail: ram.nursing@tmu.ac.in&lt;/p&gt;&lt;p&gt;You can also search for this author in: &lt;a title="PubMed" href="https://pubmed.ncbi.nlm.nih.gov/38463186/"&gt;PubMed&lt;/a&gt; &lt;a title="Google Scholar" href="https://scholar.google.com/citations?user=5IGr1E0AAAAJ&amp;amp;hl=en&amp;amp;oi=ao"&gt;Google Scholar&lt;/a&gt;&lt;/p&gt;</abstract><web_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/view/2913</web_url><pdf_url>http://ijpm.mui.ac.ir/index.php/ijpm/article/download/2913/717718754</pdf_url></Article></Articles>
