The Prevalence of Metabolic Syndrome According to Various Definitions and Hypertriglyceridemic-Waist in Malaysian Adults

Laila Ruwaida Mohd Zainuddin, Nur Firdaus Isa, Wan Manan Wan Muda, Hamid Jan Mohamed

Abstract


Objectives: Metabolic  syndrome  can  be  diagnosed  according  to several  different  criteria  such  as  the  latest  International Diabetes Federation (IDF), National Cholesterol Education Program Adult Treatment  Program  III  (NCEP ATPIII),  and World Health Organization (WHO). The objectives of this study were to determine the  prevalence  of metabolic  syndrome  and  the  concordance  between  the above mentioned definition, and hypertriglyceridemicwaist criteria.
Methods: This cross sectional study was done in Bachok, Malaysia and involved 298 respondents aged between 18 to 70 years. Multistage  random  sampling method was  used  to  identify  study  locations while  convenient  random  sampling method was  applied  to select individuals. Hypertriglyceridemic waist was defined from an internationally acceptable cut-off criterion. Kappa statistic  (κ test) was  used  to  determine  the  concordance  between  various  definitions and hypertriglyceridemic-waist.
Results: The prevalence of metabolic syndrome based on different definitions was  32.2%  (IDF),  28.5%  (NCEP ATP  III)  and  12.4% (modified WHO).  The  prevalence  of  hypertriglyceridemic-waist was 19.7% and based on  the  IDF criteria a  total of 97.5% participants  with  hypertriglyceridemic-waist  had  metabolic  syndrome.
The  IDF  criteria  showed  the  highest  concordance  with  NCEP ATPIII criteria (κ = 0.63), followed by hypertriglyceridemic-waist criteria (κ = 0.62) and WHO criteria (κ = 0.26).
Conclusions: The prevalence of metabolic  syndrome was highest using  the  IDF  criteria  compared  to  NCEP  ATPIII,  modified WHO and hypertriglyceridemic-waist. There was a good concordance  of  IDF  criteria  with  NCEP  ATP  III  and  hypertriglyceridemic-waist criteria.
Keywords:  Hypertriglyceridemic-waist,  Metabolic  syndrome,
Malaysia.

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