Can Zinc Be an Option for Prevention of Corona Virus Disease 2019?

Jamshid Roozbeh, Mohammad Hossein Imanieh, Soheil Ashkani Esfahani


Dear Editor,
The pandemic outbreak of the Corona Virus Disease 2019 (COVID‑19) claiming thousands of lives since the last months of 2019, globally, has changed the face of the world, visions and expectations from the medical
facilities, and up to now there is no definite treatment or vaccine for the infection.


Zinc; Prevention; COVID-19

Full Text:



World Health Organization. Coronavirus disease 2019

(COVID-19): situation report - 149 June 2020. Available from:


Guo YR, Cao QD, Hong ZS, Tan YY, Chen S-D, Jin HJ, et al.

The origin, transmission and clinical therapies on coronavirus

disease 2019 (COVID-19) outbreak–An update on the status. Mil

Med Res 2020;7:1-10.

Gombart AF, Pierre A, Maggini S. A review of micronutrients

and the immune system–Working in harmony to reduce the risk

of infection. Nutrients 2020;12:236.

Knoell DL, Liu M-J. Impact of zinc metabolism on innate

immune function in the setting of sepsis. Int J Vitam Nutr Res


Te Velthuis AJ, van den Worm SH, Sims AC, Baric RS,

Snijder EJ, van Hemert MJ. Zn2 + inhibits coronavirus and

arterivirus RNA polymerase activity in vitro and zinc ionophores

block the replication of these viruses in cell culture. PLoS

Pathog 2010;6:e1001176.