Association between Dietary Inflammatory Index and Risk of Cardiovascular Diseases Among Firefighters

Aniseh Vatandoost, Leila Azadbakht, Mehrnaz Morvaridi, Ali Kabir, Gholamreza Mohammadi Farsani


Background: Diet has an important role in systemic inflammation and development of cardiovascular diseases (CVD). Dietary Inflammatory Index (DII) is a new tool for evaluating the inflammatory potential of the diet. Firefighting is one of the most important occupations with stressful situations and high rates of CVD. In this study, we aimed to investigate the association between dietary inflammatory index (DII) and risk of cardiovascular diseases (CVD) among firefighters.

Methods: Two hundred and seventy‑three male firefighters aged 18–50 years in various regions of Tehran participated in this cross‑sectional study. Assessment of anthropometric, blood pressure, and biochemical parameters including glucose, total cholesterol, triglyceride, high‑density
lipoproteins (HDL‑C), low‑density lipoproteins (LDL‑C), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and high‑sensitivity C‑reactive protein (hs‑CRP) was done in all firefighters. A validated semi‑quantitative questionnaire (168 items) was used for assessment of DII.

Results: HDL (P‑value = 0.03) and hs‑CRP (P‑value = 0.05) were significantly higher in third tertile of DII scores than first. After adjustment for confounding factors, there was no significant difference in means (P‑value >0.05). The association between DII and hs‑CRP was not
significant (P‑value >0.05).

Conclusions: Participants in higher DII scores intake less polyunsaturated fatty acids (PUFAs), monounsaturated fatty acids (MUFAs), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and some antioxidant. The association between hs‑CRP and DII was not significant among firefighters.


Cardiovascular diseases;diet; firefighters; inflammation

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