Longitudinal Trend of Fasting Blood Glucose and Related Factors in Patients with Type 2 Diabetes

Zahra Khatirnamani, Enayatollah Bakhshi, Arash Naghipour, Robab Teymouri, Samaneh Hosseinzadeh

Abstract


Background: Control of diabetes plays an important role in improving complications and disabilities and quality of life. This study aimed to evaluate the 3‑year changes in fasting blood glucose (FBG) values and its related factors in patients with type 2 diabetes. Methods: In this retrospective cohort study, 500 patients with type 2 diabetes covered by the National Diabetic Prevention and Care Plan during 2013–2016 were selected based on random cluster systematic sampling. A linear mixed model was used to study changes in FBG levels and their related factors. The data were analyzed using the R3.2.0 software. Results: The patients’ mean age was 47.7 years. Among these patients, 58.6% were female, 19.8% had a history of smoking. High FBG was associated with high disease duration, high body mass index (BMI), low age, normal BMI at baseline, insulin therapy, smoking, and family history of diabetes. Trend of FBG in follow‑up was decreasing. Conclusions: Given that patients who received insulin therapy had higher mean FBG, it is recommended to examine their insulin dose and modifications should be made in terms of the patients’ needs during their continuous follow‑up. Weight loss during follow‑up and cessation of smoking indicate a favorable prognosis of disease. More attention should be paid to younger patients in care. Patients are encouraged to start treatment and care at the same time diagnose.

Keywords


Blood glucose; body mass index; diabetes mellitus type 2; insulin; smoking

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