Does Recovered COVID‑19 Patients Have Protective Reactions in Subsequent Reexposures to the Virus?

Hosein Azizi, Ali Fakhari, Elham Davtalab Esmaeili

Abstract


Protective reactions or neutralized antibody produced after coronavirus disease 2019 (COVID‑19) infection has a major impact on herd immunity induction and outbreak control. This feature potentially can open up unique opportunities for disease management.[1]

Keywords


COVID‑19; Immunity; Protective Reactions; Subsequent Reexposures

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References


Bongiovanni M, Basile F. Re‑infection by COVID‑19: A real

threat for the future management of pandemia? Infect Dis

;52:581‑2.

Wang Y, Kang H, Liu X, Tong Z: Combination of RT‑qPCR

testing and clinical features for diagnosis of COVID‑19

facilitates management of SARS‑CoV‑2 outbreak. J Med Virol

;92:538‑9.

Kang H, Wang Y, Tong Z, Liu X. Retest positive for

SARS‑CoV‑2 RNA of “recovered” patients with COVID‑19:

Persistence, sampling issues, or re‑infection? J Med Virol

;92:2263‑5.

Azizi H. Indicators for assessing the practice and

capacity of COVID‑19 surveillance system. J Marine Med

;2:53‑6.

Tian M, Long Y, Hong Y, Zhang X, Zha Y: The treatment and

follow‑up of ‘recurrence’with discharged COVID‑19 patients:

Data from Guizhou, China. Environ Microbiol 2020;22:3588‑92.

Peron JPS, Nakaya H. Susceptibility of the elderly to

SARS‑CoV‑2 infection: ACE‑2 overexpression, shedding,

and antibody‑dependent enhancement (ADE). Clinics

;75:e1912.

Bao L, Deng W, Gao H, Xiao C, Liu J, Xue J, et al. Reinfection

could not occur in SARS‑CoV‑2 infected rhesus macaques.

BioRxiv 2020. doi: 10.1101/2020.03.13.990226.

Thevarajan I, Nguyen TH, Koutsakos M, Druce J, Caly L,

van de Sandt CE, et al. Breadth of concomitant immune

responses prior to patient recovery: A case report of non‑severe

COVID‑19. Nat Med 2020;26:453‑5.

Long Q‑X, Liu B‑Z, Deng H‑J, Wu G‑C, Deng K, Chen Y‑K,

et al. Antibody responses to SARS‑CoV‑2 in patients with

COVID‑19. Nat Med 2020;26:845‑8.

To KK‑W, Tsang OT‑Y, Leung W‑S, Tam AR, Wu T‑C, Lung DC,

et al. Temporal profiles of viral load in posterior oropharyngeal

saliva samples and serum antibody responses during infection by

SARS‑CoV‑2: An observational cohort study. Lancet Infect Dis

;20:565‑74.