Relationship Between C-Reactive Protein and Physical Fitness, Physical Activity, Obesity and Selected Cardiovascular Risk Factors in Schoolchildren

Hamid Reza Sadeghipour, Ameneh Rahnama, Mohsen Salesi, Nader Rahnama, Hossein Mojtahedi


Objectives: The aim of this study was to investigate the relation
between C-reactive protein (CRP) with physical fitness, physical
activity, obesity, and selected cardiovascular risk factors in schoolchildren.
Methods: Forty-four boy schoolchildren (mean ± SD: age 10.25
± 0.75 years, height 144 ± 0.2 cm, body weight 46.1 5± 4.59 kg,
body mass index 22.16 ± 2.16 kg/m2) voluntarily participated in
this study. Physical fitness and physical activity were assessed using
the 20-meter fitness test. Adiposity was estimated using body mass
index. Blood samples were taken after an overnight fast and measured
for CRP, LDL, HDL and cholesterol. Pearson’s correlation
was calculated to determine the relations between these factors.
Results: Mean (SD) CRP concentration was 1.07 (0.82) mg/l. A
significant correlation was observed between CRP and VO2max
(r=-0.45, P= 0.001), body mass index (r=0.55, P=0.000) and cholesterol
(r=-0.35, P=0.04). No significant relation was found between
CRP and physical activity, LDL and HDL (P> 0.05).
Moreover, significant associations were observed between body
mass index and VO2max (r=-0.33, P=0.02) and physical activity
(r=-0.43, P=0.04).
Conclusions: Body mass index was the most powerful predictor
of serum concentrations of CRP in schoolchildren. It may be an
important factor to control body weight to prevent an increase in
serum CRP in children and to help the primordial prevention of
chronic diseases.
Keywords: Cardiovascular diseases, C-reactive protein, Fitness,
Body mass index.

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