The Role of Intraprostatic Inflammation in the Acute Urinary Retention

Seyed Alaeddin Asgari, Mohaddeseh Mohammadi



Introduction & objective: An estimated 70% of men aged 61-70 years and 90% of those aged 81-90 have pathological benign prostatic hyperplasia (BPH). Almost 20% of patients with lower urinary tract symptoms (LUTS) associated with BPH might also have symptoms of prostatitis. But the inter-relationship between BPH and prostatic inflammation, and how one can influence the other, is under controversy. The aim of our study was determining whether the incidence of prostatic inflammation was significantly different in patients presented with acute urinary retention (AUR) than in those presented with LUTS.

Patients & methods: This is a cross-sectional study which carried out in a hospital at Guilan, the northern province of Iran. 280 patients undergoing transurethral resection of the prostate (TURP) or open prostatectomy between 1999 and 2002 were subjects of the study. Histopathologic samples of prostate were examined for existence of (acute and/or chronic intraprostatic inflammation) ACI .

Results: 150 patients (53.6%) undertook surgery because of AUR and 130 patients (46.4%) because of  LUTS. Among them, 130 patients (46.4%) showed ACI in the pathologic examinations whereas 150 patients (53.6%) did not. The patients with AUR were significantly older than those with LUTS (P = 0.001). ACI was significantly associated with AUR (P = 0.016). The mean (SD) prostate weight was significantly higher in AUR group compared to that in the LUTS group .Also those patients who showed ACI according to pathologic examinations had heavier prostates than those who did not.

Conclusion: The main finding of the present study is that ACI may be associated with some degree of urinary obstruction and AUR.


Keywords: ACI , AUR, BPH

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