International Journal of Preventive Medicine2008-78024420130203Vitiligo Associated with Esophageal Adenocarcinoma489490ENAliAsilianImanMomeni. Momeni_i@yahoo.comParastouKhosravani20130203Vitiligo is a disease that results in depigmented areas in the skin. It may develop at any age but the average age at onset is 20 years. Association of vitiligo and melanoma has been commonly reported, but malignancies other than melanoma have been rarely associated with vitiligo. We report a 73‑year‑old patient with new onset vitiligo who developed esophageal adenocarcinoma in the following years. Keywords: Esophageal adenocarcinoma, vitiligo, thyrosinase, malignant Melanoma