Survival Rate and Predictors of Mortality among Hemodialysis Patients in West of Iran, 1996–2015

Salman Khazaei, Mehdi Yaseri, Shahrzad Nematollahi, Zahra Zobdeh, Vida Sheikh, Mohammad Ali Mansournia

Abstract


Background: Hemodialysis (HD) is one of the treatments provided to end‑stage renal disease (ESRD) patients. A few studies have investigated the survival rate of HD patients in Iran. Hence, we decided to investigate the survival rate and it is predictors among Iranian ESRD patients.

Methods: This is a retrospective cohort study conducted in 165 HD patients in Tuyserkan city (Hamadan province) during 20 years from 1996 to 2015. The checklist used to gather information was comprised of patients’ demographic and clinical information. The analysis was performed using Kaplan–Meier curves, log‑rank test, and cox regression model.

Results: The most prevalent cause of ESRD was reported to be high blood pressure (32.7%). The probability of survival rate at the end of 1st, 5th, and
10th year was 0.65, 0.16, and 0.05, respectively. Results of multivariate cox regression showed that old age, catheter vascular access, and high hemoglobin level have a negative signifcant effect on survival of HD patients (P < 0.05).

Conclusions: Overall, the survival of HD patients seems to be low in Tuyserkan as compared to other studies. Age, ESRD cause, vascular access, marital status, and hemoglobin level among other factors are proved to have a signifcant effect on survival probability.

Keywords: Cox regression models, end‑stage renal disease, hemodialysis patients, survival


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