Thyroid Cancer‑Specific Health‑Related Quality of Life Questionnaire: Psychometric Properties of the Persian Version

Mojgan Sanjari, Mahsa Esmaeeli, Habibeh Ahmadipour


Background: Adverse effects related to treatment negatively affect the quality of life of patients with thyroid cancer. The current study aimed to evaluate the psychometric properties of the Persian version of the thyroid‑cancer‑specific health‑related quality of life (TC‑specific HRQoL) questionnaire among patients with thyroid cancer in Kerman province, Iran.

Methods: This research was a cross‑sectional study conducted on 240 patients with thyroid cancer in Kerman province from 2000 to 2015. The patients were selected through the census method and were asked to complete the thyroid‑cancer‑specific quality of life questionnaire. Data were analyzed by SPSS version 19.0 and LISREL version 8.80. The reliability of the Persian version was determined by Cronbach’s a coefficient and the intraclass correlation coefficient (ICC). Exploratory and confirmatory factor analysis (CFA) was also conducted.

Results: The Cronbach’s a and ICCs were determined as 0.92 and 0.88, respectively. Five factors were extracted in the exploratory factor analysis with a total of 55.76% explained variance. Acceptable goodness of fit indices were found in CFA.

Conclusions: The Persian version of the TC‑specific HRQoL has sufficient psychometric properties and can be used to assess HRQoL among patients with thyroid cancer.


Iran; quality of life; reproducibility of results; surveys and questionnaires; thyroid neoplasms

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