The Role of Vitamins and Minerals Supplementation on COVID‑19 Prevention: Benefit or Risk?

Erika Aparecida Silveira, Patricia Constante Jaime, Matias Noll, Cesar de Oliveira


Dear Editor, In a scenario where there is a lot of uncertainty regarding SARS‑CoV‑2, vitamin and mineral supplementation have gained considerable attention due to the belief that they could prevent infection. However, the scientific evidence is tenuous with regard to their potential to prevent coronavirus disease‑2019 (COVID‑19), and reduce disease severity or mortality


Minerals; Supplementation; Vitamins; COVID‑19

Full Text:



Gombart AF, Pierre A, Maggini S. A review of micronutrients

and the immune system–working in harmony to reduce the risk

of infection. Nutrients 2020;12:236.

Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB,

Aliano JL, et al. Evidence that vitamin D supplementation could

reduce risk of influenza and COVID‑19 infections and deaths.

Nutrients 2020;12:988.

Ribeiro H, de Souza de Santana KV, Oliver SL,

de Carvalho Rondó PH, Mendes MM, Charlton K, et al. Does

vitamin D play a role in the management of Covid‑19 in Brazil?

Rev Saude Publica 2020;54:53.

Aune D, Giovannucci E, Boffetta P, Fadnes LT, Keum N, Norat T, et al. Fruit and vegetable intake and the risk of cardiovascular

disease, total cancer and all‑cause mortality—A systematic

review and dose‑response meta‑analysis of prospective studies.

Int J Epidemiol 2017;46:1029‑56.

Monteiro CA, Cannon G, Lawrence M, Costa Louzada ML,

Pereira Machado P. Ultra‑Processed Foods, Diet Quality, and

Health Using the NOVA Classification System. Roma: FAO;